6/6/2023 0 Comments Diazepam od antidoteType Small Molecule Groups Approved, Illicit, Investigational, Vet approved Structure ![]() This current development is subsequently an important addition to the rescue therapy tool chest for patients with epilepsy 7. Combining diazepam, a proven effective therapy for acute repetitive seizures, with an auto-injector designed for subcutaneous administration that is quickly and easily administered offers the potential for complete, consistent drug absorption and rapid onset of effect 7. Given diazepam's storied history as a commonly used and effective medication for a variety of indications, contemporary advancements in the formulation and administration of the agent include the development and US FDA approval of an auto-injectable formulation for the rapid treatment of uncontrolled seizures in 2015-2016 7. (From Martindale, The Extra Pharmacopoeia, 30th ed, p589) ![]() ![]() It is used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome. Its actions are mediated by enhancement of gamma-aminobutyric acid activity. Diastat, Valium, Valtoco 5 Mg Dose Kit Generic Name Diazepam DrugBank Accession Number DB00829 BackgroundĪ benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action.
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